Nimustine Hydrochloride

Catalog No. A17583

Nimustine hydrochloride is an antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine.

Technical details

Catalog Num	A17583
M. Wt	309.15
Formula	C9H14Cl2N6O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	55661-38-6
Synonyms	CS 439 HCl; CS439 HCl; CS-439 HCl; CS-439; CS439; CS 439
SMILES	O=C(NCC1=CN=C(C)N=C1N)N(CCCl)N=O.[H]Cl

Biological Activity

Solubility *

In vitro	DMSO	60 mg/mL (194.08 mM)
	Water
	Ethanol
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.35 mL	161.73 mL	323.47 mL
0.5 mM	6.47 mL	32.35 mL	64.69 mL
1 mM	3.23 mL	16.17 mL	32.35 mL
5 mM	0.65 mL	3.23 mL	6.47 mL

*The above data is based on the productmolecular weight 309.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Nimustine Hydrochloride

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions