Paritaprevir (ABT-450)

Catalog No. A17625

Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively.

Technical details

Catalog Num	A17625
M. Wt	765.88
Formula	C40H43N7O7S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1216941-48-8
Synonyms	ATB450; ABT-450; ABT 450; Paritaprevir; Veruprevir; Brand name: VIEKIRA PAK.
SMILES	O=C([C@]([C@]1([H])/C=C\CCCCC[C@@H]2NC(C3=NC=C(C)N=C3)=O)(C1)NC([C@@](C[C@@H](OC4=C5C=CC=CC5=C(C=CC=C6)C6=N4)C7)([H])N7C2=O)=O)NS(=O)(C8CC8)=O

Biological Activity

Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively.

Solubility *

In vitro	DMSO	97 mg/mL (126.64 mM)
	Water
	Ethanol
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	13.06 mL	65.28 mL	130.57 mL
0.5 mM	2.61 mL	13.06 mL	26.11 mL
1 mM	1.31 mL	6.53 mL	13.06 mL
5 mM	0.26 mL	1.31 mL	2.61 mL

*The above data is based on the productmolecular weight 765.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Paritaprevir (ABT-450)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions