Dihydroergotamine Mesylate

Catalog No. A17764

Dihydroergotamine Mesylate, also known as DHE or Migranal, is an ergot alkaloid used to treat migraines. It has similar actions to the triptans, acting as an agonist to the serotonin receptors and causing vasoconstriction of the intracranial blood vessels, but also interacts centrally with dopamine and adrenergic receptors.

Technical details

Catalog Num	A17764
M. Wt	679.78
Formula	C34H41N5O8S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	6190-39-2
Synonyms	Dihydroergotamine Mesylate; DHE; Migranal;
SMILES	O=C([C@@H](CN(C)[C@]1([H])C2)C[C@]1([H])C3=C4C2=CNC4=CC=C3)N[C@](C(N5[C@H]6CC7=CC=CC=C7)=O)(C)O[C@@]5(O)[C@]8([H])CCCN8C6=O.OS(=O)(C)=O

Biological Activity

Solubility *

In vitro	DMSO	99 mg/mL (145.63 mM)
	Water
	Ethanol
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.71 mL	73.55 mL	147.11 mL
0.5 mM	2.94 mL	14.71 mL	29.42 mL
1 mM	1.47 mL	7.36 mL	14.71 mL
5 mM	0.29 mL	1.47 mL	2.94 mL

*The above data is based on the productmolecular weight 679.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Dihydroergotamine Mesylate

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions