Vonoprazan free base
Catalog No. A18007
Vonoprazan (TAK-438 free base) is an orally active potassium-competitive acid blocker which inhibits H+, K+-ATPase activity with an IC50 of 19 nM.
| Catalog Num | A18007 |
|---|---|
| M. Wt | 345.39 |
| Formula | C17H16FN3O2S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 881681-00-1 |
| Synonyms | TAK-438 free base, TAK438, TAK 438 |
| SMILES | O=S(N1C=C(CNC)C=C1C2=CC=CC=C2F)(C3=CC=CN=C3)=O |
Vonoprazan (TAK-438 free base) is an orally active potassium-competitive acid blocker which inhibits H+, K+-ATPase activity with an IC50 of 19 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.95 mL | 144.76 mL | 289.53 mL |
| 0.5 mM | 5.79 mL | 28.95 mL | 57.91 mL |
| 1 mM | 2.9 mL | 14.48 mL | 28.95 mL |
| 5 mM | 0.58 mL | 2.9 mL | 5.79 mL |
*The above data is based on the productmolecular weight 345.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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