Niraparib hydrochloride
Catalog No. A18018
Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively.
| Catalog Num | A18018 |
|---|---|
| M. Wt | 356.85 |
| Formula | C19H21ClN4O |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1038915-64-8 |
| Synonyms | MK-4827 hydrochloride, MK4827, MK 4827 |
| SMILES | NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.Cl |
Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.02 mL | 140.11 mL | 280.23 mL |
| 0.5 mM | 5.6 mL | 28.02 mL | 56.05 mL |
| 1 mM | 2.8 mL | 14.01 mL | 28.02 mL |
| 5 mM | 0.56 mL | 2.8 mL | 5.6 mL |
*The above data is based on the productmolecular weight 356.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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