Cobimetinib hemifumarate
Catalog No. A18033
Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM.
| Catalog Num | A18033 |
|---|---|
| M. Wt | 647.38 |
| Formula | C25H25F3IN3O6 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1369665-02-0 |
| Synonyms | GDC-0973 hemifumarate, GDC0973, GDC 0973; XL-518 hemifumarate, XL518, XL 518 |
| SMILES | OC1([C@H]2NCCCC2)CN(C1)C(C3=C(C(F)=C(C=C3)F)NC4=C(C=C(C=C4)I)F)=O.O=C(O)/C=C/C(O)=O.[0.5] |
Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.45 mL | 77.23 mL | 154.47 mL |
| 0.5 mM | 3.09 mL | 15.45 mL | 30.89 mL |
| 1 mM | 1.54 mL | 7.72 mL | 15.45 mL |
| 5 mM | 0.31 mL | 1.54 mL | 3.09 mL |
*The above data is based on the productmolecular weight 647.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
ADOOQ 产品质量保证
We promise all products to perform as described.