Tafamidis meglumine
Catalog No. A18045
Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM.
| Catalog Num | A18045 |
|---|---|
| M. Wt | 503.33 |
| Formula | C21H24Cl2N2O8 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 951395-08-7 |
| Synonyms | Fx-1006A, Fx1006A, Fx 1006A |
| SMILES | O=C(C1=CC=C2N=C(C3=CC(Cl)=CC(Cl)=C3)OC2=C1)O.O[C@@H]([C@@H]([C@@H](CO)O)O)[C@@H](O)CNC |
Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.87 mL | 99.34 mL | 198.68 mL |
| 0.5 mM | 3.97 mL | 19.87 mL | 39.74 mL |
| 1 mM | 1.99 mL | 9.93 mL | 19.87 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.97 mL |
*The above data is based on the productmolecular weight 503.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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