Tinostamustine (EDO-S101)

Catalog No. A18342

EDO-S101 is a pan HDAC inhibitor; inhibits HDAC1, HDAC2 and HDAC3 with IC50 values of 9, 9 and 25 nM, respectively.

Technical details

Catalog Num	A18342
M. Wt	415.359
Formula	C19H28Cl2N4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1236199-60-2
Synonyms	EDOS101, EDO S101
SMILES	O=C(NO)CCCCCCC1=NC2=CC(N(CCCl)CCCl)=CC=C2N1C

Biological Activity

EDO-S101 is a pan HDAC inhibitor; inhibits HDAC1, HDAC2 and HDAC3 with IC50 values of 9, 9 and 25 nM, respectively.

Solubility *

In vitro	DMSO	12 mg/mL (28.89 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (4.81 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.08 mL	120.38 mL	240.76 mL
0.5 mM	4.82 mL	24.08 mL	48.15 mL
1 mM	2.41 mL	12.04 mL	24.08 mL
5 mM	0.48 mL	2.41 mL	4.82 mL

*The above data is based on the productmolecular weight 415.359. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Tinostamustine (EDO-S101)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions