GW-870086

Catalog No. A18343

GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB.

Technical details

Catalog Num	A18343
M. Wt	559.64
Formula	C31H39F2NO6
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	827319-43-7
Synonyms	GW 870086 , GW870086
SMILES	C[C@@]12[C@](C(OCC#N)=O)(OC(C3C(C)(C)C3(C)C)=O)[C@H](C)C[C@@]1([H])[C@]4([H])C[C@H](F)C5=CC(C=C[C@]5(C)[C@@]4(F)[C@@H](O)C2)=O

Biological Activity

GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.87 mL	89.34 mL	178.69 mL
0.5 mM	3.57 mL	17.87 mL	35.74 mL
1 mM	1.79 mL	8.93 mL	17.87 mL
5 mM	0.36 mL	1.79 mL	3.57 mL

*The above data is based on the productmolecular weight 559.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

GW-870086

Technical details

Biological Activity

Preparing Stock Solutions