MIK665

Catalog No. A18362

MIK665 (S-64315) is a special Mcl-1 inhibitor extracted from patent WO2016207225A1, compound Preparation 13, has an IC50 of 1.81 nM.

Technical details

Catalog Num	A18362
M. Wt	875.41
Formula	C47H44ClFN6O6S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1799631-75-6
Synonyms	MIK665; MIK-665; MIK 665; S 64315; S-64315; S64315
SMILES	OC([C@@H](CC(C=CC=C1)=C1OCC2=CC=NC(C3=CC=CC=C3OC)=N2)OC4=C5[C@]([C@]6=C(C)C(Cl)=C(OCCN7CCN(C)CC7)C=C6)=C(C8=CC=C(F)C=C8)SC5=NC=N4)=O

Biological Activity

MIK665 (S-64315) is a special Mcl-1 inhibitor extracted from patent WO2016207225A1, compound Preparation 13, has an IC50 of 1.81 nM.

Solubility *

In vitro	DMSO	92 mg/mL (105.09 mM)
	Water	Insoluble
	Ethanol	<1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	11.42 mL	57.12 mL	114.23 mL
0.5 mM	2.28 mL	11.42 mL	22.85 mL
1 mM	1.14 mL	5.71 mL	11.42 mL
5 mM	0.23 mL	1.14 mL	2.28 mL

*The above data is based on the productmolecular weight 875.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

MIK665

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions