PROTAC Mcl1 degrader-1
Catalog No. A18373
PROTAC Mcl1 degrader-1 (compound C3), a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 μM.
| Catalog Num | A18373 |
|---|---|
| M. Wt | 909.84 |
| Formula | C45H45BrN6O8S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2163793-38-0 |
| Synonyms | |
| SMILES | O=C(C1=CC=CC(NCCCCCCNC(CCCCC(NCCN2C(C3=C4C(C2=O)=CC=C(C4=CC=C3)SC5=CC=C(C=C5)Br)=O)=O)=O)=C1C6=O)N6C7CCC(NC7=O)=O |
PROTAC Mcl1 degrader-1 (compound C3), a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.99 mL | 54.95 mL | 109.91 mL |
| 0.5 mM | 2.2 mL | 10.99 mL | 21.98 mL |
| 1 mM | 1.1 mL | 5.5 mL | 10.99 mL |
| 5 mM | 0.22 mL | 1.1 mL | 2.2 mL |
*The above data is based on the productmolecular weight 909.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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