Mcl1-IN-12

Catalog No. A18379

Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity.

Technical details

Catalog Num	A18379
M. Wt	803
Formula	C45H46N4O6S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	2042211-12-9
Synonyms
SMILES	O=C(NS(=O)(C1=CC=C(NCCSC2=CC=CC=C2)C([N+]([O-])=O)=C1)=O)C3=CC=C(NC(C(C=C4)=CC=C4C(C5=C(C)C=C(C(C)(C)CCC6(C)C)C6=C5)=C)=O)C=C3

Biological Activity

Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.45 mL	62.27 mL	124.53 mL
0.5 mM	2.49 mL	12.45 mL	24.91 mL
1 mM	1.25 mL	6.23 mL	12.45 mL
5 mM	0.25 mL	1.25 mL	2.49 mL

*The above data is based on the productmolecular weight 803. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Mcl1-IN-12

Technical details

Biological Activity

Preparing Stock Solutions