KRAS G12C inhibitor 16

Catalog No. A18444

KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 39, has an IC50 of 97 nM.
Catalog Num A18444
M. Wt 453.89
Formula C24H21ClFN3O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2349392-79-4
Synonyms
SMILES OC1=C(C2=C(C)C(N=CC3=C4N5[C@H](CN(C(C=C)=O)CC5)CO3)=C4C=C2Cl)C(F)=CC=C1
KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 39, has an IC50 of 97 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.03 mL 110.16 mL 220.32 mL
0.5 mM 4.41 mL 22.03 mL 44.06 mL
1 mM 2.2 mL 11.02 mL 22.03 mL
5 mM 0.44 mL 2.2 mL 4.41 mL

*The above data is based on the productmolecular weight 453.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.