HS-1371

Catalog No. A18653

HS-1371 is a potent and ATP-competitive receptor-interacting protein kinase 3 (RIP3) inhibitor with an IC50 of 20.8?nM.
Catalog Num A18653
M. Wt 384.47
Formula C24H24N4O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2158197-70-5
Synonyms HS1371, HS 1371
SMILES CC1=CC=C(OC2=CC=NC3=CC(C4=CN(C5CCNCC5)N=C4)=CC=C23)C=C1
HS-1371 is a potent and ATP-competitive receptor-interacting protein kinase 3 (RIP3) inhibitor with an IC50 of 20.8?nM.
In vitro DMSO 12 mg/mL (31.21 mM)
Water Insoluble
Ethanol 4 mg/mL (10.4 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.01 mL 130.05 mL 260.1 mL
0.5 mM 5.2 mL 26.01 mL 52.02 mL
1 mM 2.6 mL 13 mL 26.01 mL
5 mM 0.52 mL 2.6 mL 5.2 mL

*The above data is based on the productmolecular weight 384.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.