BRD4 Inhibitor-10

Catalog No. A18679

BRD4 Inhibitor-10 is a potent BRD4-BD1 inhibitor extracted from patent WO2015022332A1, Compound II-25, has an IC50 of 8 nM.

Technical details

Catalog Num	A18679
M. Wt	429.51
Formula	C25H27N5O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1660117-38-3
Synonyms
SMILES	CN1C(C(C)=CC(C2=NC3=CN=C(C=C3N2[C@H](C4=CC=CC=C4)C)C5CCOCC5)=N1)=O

Biological Activity

BRD4 Inhibitor-10 is a potent BRD4-BD1 inhibitor extracted from patent WO2015022332A1, Compound II-25, has an IC50 of 8 nM.

Solubility *

In vitro	DMSO	83 mg/mL (193.24 mM)
	Water	Insoluble
	Ethanol	83 mg/mL (193.24 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.28 mL	116.41 mL	232.82 mL
0.5 mM	4.66 mL	23.28 mL	46.56 mL
1 mM	2.33 mL	11.64 mL	23.28 mL
5 mM	0.47 mL	2.33 mL	4.66 mL

*The above data is based on the productmolecular weight 429.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

BRD4 Inhibitor-10

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions