BPN-15606

Catalog No. A18681

BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively.
Catalog Num A18681
M. Wt 418.47
Formula C23H23FN6O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1914989-49-3
Synonyms BPN15606, BPN 15606
SMILES CC1=CC(C2=NC(OC)=C(N3C=C(C)N=C3)C=C2)=NN=C1N[C@H](C4=CC=C(F)C=C4)C
BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.9 mL 119.48 mL 238.97 mL
0.5 mM 4.78 mL 23.9 mL 47.79 mL
1 mM 2.39 mL 11.95 mL 23.9 mL
5 mM 0.48 mL 2.39 mL 4.78 mL

*The above data is based on the productmolecular weight 418.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.