PROTAC FLT-3 degrader 1
Catalog No. A18682
PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction.
| Catalog Num | A18682 |
|---|---|
| M. Wt | 1020.23 |
| Formula | C52H61N9O9S2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2230826-81-8 |
| Synonyms | |
| SMILES | O=C(N[C@@H](C(C)(C)C)C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)CCOCCOCCOC4=CC5=C(N6C(S5)=NC(C7=CC=C(NC(NC8=NOC(C(C)(C)C)=C8)=O)C=C7)=C6)C=C4 |
PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 9.8 mL | 49.01 mL | 98.02 mL |
| 0.5 mM | 1.96 mL | 9.8 mL | 19.6 mL |
| 1 mM | 0.98 mL | 4.9 mL | 9.8 mL |
| 5 mM | 0.2 mL | 0.98 mL | 1.96 mL |
*The above data is based on the productmolecular weight 1020.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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