CM-579
Catalog No. A18692
CM-579 is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells.
Catalog Num | A18692 |
---|---|
M. Wt | 492.65 |
Formula | C27H35N4O3 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1846570-40-8 |
Synonyms | CM579, CM 579 |
SMILES | COC1=C(OCCCN2CCCC2)C=C(N=C(C3=CC=C(C)O3)C=C4NC5CCC[N]C5)C4=C1 |
CM-579 is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.3 mL | 101.49 mL | 202.98 mL |
0.5 mM | 4.06 mL | 20.3 mL | 40.6 mL |
1 mM | 2.03 mL | 10.15 mL | 20.3 mL |
5 mM | 0.41 mL | 2.03 mL | 4.06 mL |
*The above data is based on the productmolecular weight 492.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.