WR99210

Catalog No. A18837

WR99210 is a effective inhibitor of dihydrofolate reductase (DHFR) with an IC50 of <0.075 nM. WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains.
Catalog Num A18837
M. Wt 394.68
Formula C14H18Cl3N5O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 47326-86-3
Synonyms WR 99210, WR-99210
SMILES CC1(N=C(N=C(N1OCCCOC2=C(C=C(C(Cl)=C2)Cl)Cl)N)N)C
WR99210 is a effective inhibitor of dihydrofolate reductase (DHFR) with an IC50 of <0.075 nM. WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.34 mL 126.68 mL 253.37 mL
0.5 mM 5.07 mL 25.34 mL 50.67 mL
1 mM 2.53 mL 12.67 mL 25.34 mL
5 mM 0.51 mL 2.53 mL 5.07 mL

*The above data is based on the productmolecular weight 394.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.