PROTAC MDM2 Degrader-1

Catalog No. A18897

PROTAC MDM2 Degrader-1 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-1 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase.
Catalog Num A18897
M. Wt 1463.33
Formula C74H84Cl4N10O13
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2249944-98-5
Synonyms 0
SMILES O=C(N1CC(N(CC(NCCCOCCOCCOCCCNC(CN2C(CN(C(N3[C@@H](C4=CC=C(Cl)C=C4)[C@@H](C5=CC=C(Cl)C=C5)N=C3C6=C(C=C(OC)C=C6)OC(C)C)=O)CC2)=O)=O)=O)CC1)=O)N7[C@@H](C8=CC=C(Cl)C=C8)[C@@H](C9=CC=C(Cl)C=C9)N=C7C%10=C(C=C(OC)C=C%10)OC(C)C
PROTAC MDM2 Degrader-1 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-1 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 6.83 mL 34.17 mL 68.34 mL
0.5 mM 1.37 mL 6.83 mL 13.67 mL
1 mM 0.68 mL 3.42 mL 6.83 mL
5 mM 0.14 mL 0.68 mL 1.37 mL

*The above data is based on the productmolecular weight 1463.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.