NaV1.7 inhibitor-1

Catalog No. A18933

NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5.
Catalog Num A18933
M. Wt 435.55
Formula C23H30FNO4S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1494585-79-3
Synonyms
SMILES FC1=CC(OCC2(C)CCC3(CC3)CC2)=C(C4CC4)C=C1C(NS(C5CC5)(=O)=O)=O
NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.96 mL 114.8 mL 229.59 mL
0.5 mM 4.59 mL 22.96 mL 45.92 mL
1 mM 2.3 mL 11.48 mL 22.96 mL
5 mM 0.46 mL 2.3 mL 4.59 mL

*The above data is based on the productmolecular weight 435.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.