PROTAC FAK degrader 1
Catalog No. A18946
PROTAC FAK degrader 1 is a selective and potent focal adhesion kinase (Fak) degrader with an IC50 of 6.5 nM, DC50 of 3 nM.
| Catalog Num | A18946 |
|---|---|
| M. Wt | 996.13 |
| Formula | C47H56F3N9O8S2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2301916-69-6 |
| Synonyms | 0 |
| SMILES | O=C(N[C@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)C(C)(C)C)CCOCCOC4=CC=C(NC5=NC(NCC6=CC=CC(N(C)S(C)(=O)=O)=C6)=C(C(F)(F)F)C=N5)C=C4 |
PROTAC FAK degrader 1 is a selective and potent focal adhesion kinase (Fak) degrader with an IC50 of 6.5 nM, DC50 of 3 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.04 mL | 50.19 mL | 100.39 mL |
| 0.5 mM | 2.01 mL | 10.04 mL | 20.08 mL |
| 1 mM | 1 mL | 5.02 mL | 10.04 mL |
| 5 mM | 0.2 mL | 1 mL | 2.01 mL |
*The above data is based on the productmolecular weight 996.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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