GNE-955

Catalog No. A19243

GNE-955 is a potent and orally active pan Pim kinase inhibitor with Kis of 0.018, 0.11, 0.08 nM for Pim1, Pim2, Pim3, respectively.
Catalog Num A19243
M. Wt 416.48
Formula C22H24N8O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1527523-39-2
Synonyms GNE 955; GNE955
SMILES CC1=CN=CC(C2=CC3=C(C=NN3C4=CC=C(OC)C(N5CCC[C@H](N)C5)=N4)C=N2)=N1
GNE-955 is a potent and orally active pan Pim kinase inhibitor with Kis of 0.018, 0.11, 0.08 nM for Pim1, Pim2, Pim3, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.01 mL 120.05 mL 240.11 mL
0.5 mM 4.8 mL 24.01 mL 48.02 mL
1 mM 2.4 mL 12.01 mL 24.01 mL
5 mM 0.48 mL 2.4 mL 4.8 mL

*The above data is based on the productmolecular weight 416.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.