GNE-955
Catalog No. A19243
GNE-955 is a potent and orally active pan Pim kinase inhibitor with Kis of 0.018, 0.11, 0.08 nM for Pim1, Pim2, Pim3, respectively.
Catalog Num | A19243 |
---|---|
M. Wt | 416.48 |
Formula | C22H24N8O |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1527523-39-2 |
Synonyms | GNE 955; GNE955 |
SMILES | CC1=CN=CC(C2=CC3=C(C=NN3C4=CC=C(OC)C(N5CCC[C@H](N)C5)=N4)C=N2)=N1 |
GNE-955 is a potent and orally active pan Pim kinase inhibitor with Kis of 0.018, 0.11, 0.08 nM for Pim1, Pim2, Pim3, respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.01 mL | 120.05 mL | 240.11 mL |
0.5 mM | 4.8 mL | 24.01 mL | 48.02 mL |
1 mM | 2.4 mL | 12.01 mL | 24.01 mL |
5 mM | 0.48 mL | 2.4 mL | 4.8 mL |
*The above data is based on the productmolecular weight 416.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.