AD80

Catalog No. A19332

AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity.

Technical details

Catalog Num	A19332
M. Wt	473.43
Formula	C22H19F4N7O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1384071-99-1
Synonyms	AD 80, AD-80
SMILES	O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C3=NN(C(C)C)C4=NC=NC(N)=C43)C=C2

Biological Activity

AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity.

Solubility *

In vitro (25°C)	DMSO	91 mg/mL (192.21 mM)
	Water	Insoluble
	Ethanol	91 mg/mL
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.12 mL	105.61 mL	211.22 mL
0.5 mM	4.22 mL	21.12 mL	42.24 mL
1 mM	2.11 mL	10.56 mL	21.12 mL
5 mM	0.42 mL	2.11 mL	4.22 mL

*The above data is based on the productmolecular weight 473.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

AD80

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions