GDC-0077
Catalog No. A19494
GDC-0077 (RG6114) is a potent, orally available, and selective PI3Kα inhibitor (IC50=0.038 nM).
| Catalog Num | A19494 |
|---|---|
| M. Wt | 407.37 |
| Formula | C18H19F2N5O4 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2060571-02-8 |
| Synonyms | RG6114, RG 6114, RG-6114; GDC-0077, GDC0077, GDC 0077 |
| SMILES | C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1 |
GDC-0077 (RG6114) is a potent, orally available, and selective PI3Kα inhibitor (IC50=0.038 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.55 mL | 122.74 mL | 245.48 mL |
| 0.5 mM | 4.91 mL | 24.55 mL | 49.1 mL |
| 1 mM | 2.45 mL | 12.27 mL | 24.55 mL |
| 5 mM | 0.49 mL | 2.45 mL | 4.91 mL |
*The above data is based on the productmolecular weight 407.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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