SNIPER(ABL)-058
Catalog No. A19616
SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM.
| Catalog Num | A19616 |
|---|---|
| M. Wt | 1150.39 |
| Formula | C62H75N11O9S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2222354-61-0 |
| Synonyms | |
| SMILES | CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCOC4=CC(C(C5=CSC([C@H]6N(C([C@H](C7CCCCC7)NC([C@H](C)NC)=O)=O)CCC6)=N5)=O)=CC=C4)=O)CC3)C=C2)=O)C=C1NC8=NC=CC(C9=CC=CN=C9)=N8 |
SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 8.69 mL | 43.46 mL | 86.93 mL |
| 0.5 mM | 1.74 mL | 8.69 mL | 17.39 mL |
| 1 mM | 0.87 mL | 4.35 mL | 8.69 mL |
| 5 mM | 0.17 mL | 0.87 mL | 1.74 mL |
*The above data is based on the productmolecular weight 1150.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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