PI3K/mTOR Inhibitor-2
Catalog No. A19621
PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR. Antitumor activity.
| Catalog Num | A19621 |
|---|---|
| M. Wt | 478.86 |
| Formula | C20H13ClF2N4O4S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1848242-58-9 |
| Synonyms | |
| SMILES | FC1=CC(F)=C(S(=O)(NC2=CC(C(C=C3)=CN4C3=NC=C(Cl)C4=O)=CN=C2OC)=O)C=C1 |
PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR. Antitumor activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.88 mL | 104.41 mL | 208.83 mL |
| 0.5 mM | 4.18 mL | 20.88 mL | 41.77 mL |
| 1 mM | 2.09 mL | 10.44 mL | 20.88 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.18 mL |
*The above data is based on the productmolecular weight 478.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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