GeA-69

Catalog No. A19705

GeA-69 is a selective, highly cell permeable allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2, with a Kd of 2.1 ?M.

Technical details

Catalog Num	A19705
M. Wt	300.35
Formula	C20H16N2O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	2143475-98-1
Synonyms	GeA69; GeA 69
SMILES	CC(NC1=CC=CC=C1C2=CC=CC3=C2NC4=C3C=CC=C4)=O

Biological Activity

GeA-69 is a selective, highly cell permeable allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2, with a Kd of 2.1 ?M.

Solubility *

In vitro	DMSO	52 mg/mL (173.13 mM)
	Water	Insoluble
	Ethanol	9 mg/mL (29.96 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.29 mL	166.47 mL	332.94 mL
0.5 mM	6.66 mL	33.29 mL	66.59 mL
1 mM	3.33 mL	16.65 mL	33.29 mL
5 mM	0.67 mL	3.33 mL	6.66 mL

*The above data is based on the productmolecular weight 300.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

GeA-69

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions