CG-806
Catalog No. A19814
CG-806 is an orally active, potent and non-covalent pan-FLT3/pan-BTK inhibitor with an IC50 of 0.08 μM for FLT3. CG-806 has an IC50 of 11 nM against FLT3 wild type (WT)-transfected Ba/F3 cells.
| Catalog Num | A19814 |
|---|---|
| M. Wt | 509.45 |
| Formula | C26H19F4N5O2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1370466-81-1 |
| Synonyms | CG 806; CG806; CG-026806; CG 026806; CG026806 |
| SMILES | O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(C3=CC=C(C4=NC=C(C)N4)C5=C3CNC5=O)C(F)=C2 |
CG-806 is an orally active, potent and non-covalent pan-FLT3/pan-BTK inhibitor with an IC50 of 0.08 μM for FLT3. CG-806 has an IC50 of 11 nM against FLT3 wild type (WT)-transfected Ba/F3 cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.63 mL | 98.15 mL | 196.29 mL |
| 0.5 mM | 3.93 mL | 19.63 mL | 39.26 mL |
| 1 mM | 1.96 mL | 9.81 mL | 19.63 mL |
| 5 mM | 0.39 mL | 1.96 mL | 3.93 mL |
*The above data is based on the productmolecular weight 509.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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