TAK-981

Catalog No. A20002

TAK-981 is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities.

Technical details

Catalog Num	A20002
M. Wt	578.1
Formula	C25H28ClN5O5S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1858276-04-6
Synonyms	TAK981, TAK 981
SMILES	O=S(OC[C@@H]1[C@@H](O)C[C@H](NC2=NC=NC=C2C(C3=CC([C@@H]4NCCC5=C4C=C(Cl)C=C5)=C(C)S3)=O)C1)(N)=O

Biological Activity

TAK-981 is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities.

Solubility *

In vitro	DMSO	97 mg/mL (167.79 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.3 mL	86.49 mL	172.98 mL
0.5 mM	3.46 mL	17.3 mL	34.6 mL
1 mM	1.73 mL	8.65 mL	17.3 mL
5 mM	0.35 mL	1.73 mL	3.46 mL

*The above data is based on the productmolecular weight 578.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

TAK-981

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions