IACS-8968
Catalog No. A20020
IACS-8968 (IDO/TDO Inhibitor) is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively.
| Catalog Num | A20020 |
|---|---|
| M. Wt | 381.35 |
| Formula | C17H18F3N5O2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2144425-14-7 |
| Synonyms | IDO/TDO Inhibitor, IACS8968, IACS 8968 |
| SMILES | O=C(N1)NC2(C(C)(C)CN(C3=CC(C(F)(F)F)=CC4=CN=CN34)CC2)C1=O |
IACS-8968 (IDO/TDO Inhibitor) is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.22 mL | 131.11 mL | 262.23 mL |
| 0.5 mM | 5.24 mL | 26.22 mL | 52.45 mL |
| 1 mM | 2.62 mL | 13.11 mL | 26.22 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.24 mL |
*The above data is based on the productmolecular weight 381.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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