PI3K/mTOR Inhibitor-1
Catalog No. A20055
PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual PI3K/mTOR inhibitor with IC50s of 20/376/204/46 nM and 186 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ and mTOR, respectively. Antitumor activity.
| Catalog Num | A20055 |
|---|---|
| M. Wt | 407.46 |
| Formula | C18H22FN5O3S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1949802-49-6 |
| Synonyms | |
| SMILES | NC1=CC(F)=C(C2=CC(C3(CC3)S(=O)(C)=O)=NC(N4[C@@H](C)COCC4)=N2)C=N1 |
PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual PI3K/mTOR inhibitor with IC50s of 20/376/204/46 nM and 186 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ and mTOR, respectively. Antitumor activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.54 mL | 122.71 mL | 245.42 mL |
| 0.5 mM | 4.91 mL | 24.54 mL | 49.08 mL |
| 1 mM | 2.45 mL | 12.27 mL | 24.54 mL |
| 5 mM | 0.49 mL | 2.45 mL | 4.91 mL |
*The above data is based on the productmolecular weight 407.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Contact information
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