DC1SMe
Catalog No. A20181
DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer.
| Catalog Num | A20181 |
|---|---|
| M. Wt | 684.23 |
| Formula | C35H30ClN5O4S2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 501666-85-9 |
| Synonyms | |
| SMILES | O=C(C(N1)=CC2=C1C=CC(NC(CCSSC)=O)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(O)C7=CC=CC=C67)=O)=C4)C=C3 |
DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.61 mL | 73.07 mL | 146.15 mL |
| 0.5 mM | 2.92 mL | 14.61 mL | 29.23 mL |
| 1 mM | 1.46 mL | 7.31 mL | 14.61 mL |
| 5 mM | 0.29 mL | 1.46 mL | 2.92 mL |
*The above data is based on the productmolecular weight 684.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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