SAR-20347

Catalog No. A20380

SAR-20347 is an inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50s of 0.6, 23, 26 and 41 nM, respectively.
Catalog Num A20380
M. Wt 444.84
Formula C21H18ClFN4O4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1450881-55-6
Synonyms SAR20347, SAR 20347
SMILES O=C(C1=C(NC2=CC=C(C(N3CCOCC3)=O)C=C2)OC(C4=C(F)C=CC=C4Cl)=N1)N
SAR-20347 is an inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50s of 0.6, 23, 26 and 41 nM, respectively.
In vitro DMSO 77 mg/mL (173.09 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.48 mL 112.4 mL 224.8 mL
0.5 mM 4.5 mL 22.48 mL 44.96 mL
1 mM 2.25 mL 11.24 mL 22.48 mL
5 mM 0.45 mL 2.25 mL 4.5 mL

*The above data is based on the productmolecular weight 444.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.