GGTI298
Catalog No. A20418
GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively.
| Catalog Num | A20418 |
|---|---|
| M. Wt | 479.63 |
| Formula | C27H33N3O3S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 180977-44-0 |
| Synonyms | GGTI 298, GGTI-298 |
| SMILES | CC(C)C[C@@H](C(OC)=O)NC(C1=CC=C(NC[C@@H](N)CS)C=C1C2=C3C=CC=CC3=CC=C2)=O |
GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.85 mL | 104.25 mL | 208.49 mL |
| 0.5 mM | 4.17 mL | 20.85 mL | 41.7 mL |
| 1 mM | 2.08 mL | 10.42 mL | 20.85 mL |
| 5 mM | 0.42 mL | 2.08 mL | 4.17 mL |
*The above data is based on the productmolecular weight 479.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
ADOOQ 产品质量保证
We promise all products to perform as described.