GDC-0326

Catalog No. A20437

GDC-0326 is a potent and selective PI3Kα inhibitor with a Ki of 0.2 nM.

Technical details

Catalog Num	A20437
M. Wt	382.42
Formula	C19H22N6O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1282514-88-8
Synonyms	GDC0326, GDC 0326
SMILES	C[C@H](OC1=CC=C2C3=NC(C4=NC=NN4C(C)C)=CN3CCOC2=C1)C(N)=O

Biological Activity

GDC-0326 is a potent and selective PI3Kα inhibitor with a Ki of 0.2 nM.

Solubility *

In vitro	DMSO	72 mg/mL (188.27 mM)
	Water	Insoluble
	Ethanol	18 mg/mL (47.07 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.15 mL	130.75 mL	261.49 mL
0.5 mM	5.23 mL	26.15 mL	52.3 mL
1 mM	2.61 mL	13.07 mL	26.15 mL
5 mM	0.52 mL	2.61 mL	5.23 mL

*The above data is based on the productmolecular weight 382.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

GDC-0326

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions