NCB-0846

Catalog No. A20535

NCB-0846 is an orally available TNIK inhibitor with an IC50 of 21?nM.
Catalog Num A20535
M. Wt 375.42
Formula C21H21N5O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1792999-26-8
Synonyms NCB 0846, NCB0846
SMILES O[C@@H](CC1)CC[C@@H]1OC2=CC=CC(C=N3)=C2N=C3NC4=CC=C(N=CN5)C5=C4
NCB-0846 is an orally available TNIK inhibitor with an IC50 of 21?nM.
In vitro DMSO Warmed: 70 mg/mL (186.45 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.64 mL 133.18 mL 266.37 mL
0.5 mM 5.33 mL 26.64 mL 53.27 mL
1 mM 2.66 mL 13.32 mL 26.64 mL
5 mM 0.53 mL 2.66 mL 5.33 mL

*The above data is based on the productmolecular weight 375.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.