sulfo-SPDB-DM4

Catalog No. A20566

sulfo-SPDB-DM4 is a drug-linker conjugate for ADC by using the maytansinebased payload (DM4, an antitubulin agent) via the sulfo-SPDB linker.

Technical details

Catalog Num	A20566
M. Wt	1075.66
Formula	C46H63ClN4O17S3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1626359-59-8
Synonyms
SMILES	C[C@]1([C@@](CC(N(C(C=C2C=C3OC)=C3Cl)C)=O)([H])OC([C@H](C)N(C)C(CCC(C)(C)SSCCC(S(=O)(O)=O)C(ON(C4=O)C(CC4)=O)=O)=O)=O)[C@H]([C@@H]([C@](OC5=O)([H])C[C@]([C@](/C=C/C=C(C)/C2)([H])OC)(N5)O)C)O1

Biological Activity

sulfo-SPDB-DM4 is a drug-linker conjugate for ADC by using the maytansinebased payload (DM4, an antitubulin agent) via the sulfo-SPDB linker.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	9.3 mL	46.48 mL	92.97 mL
0.5 mM	1.86 mL	9.3 mL	18.59 mL
1 mM	0.93 mL	4.65 mL	9.3 mL
5 mM	0.19 mL	0.93 mL	1.86 mL

*The above data is based on the productmolecular weight 1075.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

sulfo-SPDB-DM4

Technical details

Biological Activity

Preparing Stock Solutions