JQ-1 (carboxylic acid)
Catalog No. A20579
JQ-1 carboxylic acid is a highly potent, selective and cell-permeable BRD4 inhibitor with IC50s of 77 nM and 33 nM for BRD4(1) and BRD4(2), respectively.
| Catalog Num | A20579 |
|---|---|
| M. Wt | 400.88 |
| Formula | C19H17ClN4O2S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 202592-23-2 |
| Synonyms | |
| SMILES | ClC1=CC=C(C(C2=C(N3C4=NN=C3C)SC(C)=C2C)=N[C@H]4CC(O)=O)C=C1 |
JQ-1 carboxylic acid is a highly potent, selective and cell-permeable BRD4 inhibitor with IC50s of 77 nM and 33 nM for BRD4(1) and BRD4(2), respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.95 mL | 124.73 mL | 249.45 mL |
| 0.5 mM | 4.99 mL | 24.95 mL | 49.89 mL |
| 1 mM | 2.49 mL | 12.47 mL | 24.95 mL |
| 5 mM | 0.5 mL | 2.49 mL | 4.99 mL |
*The above data is based on the productmolecular weight 400.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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