Rimacalib

Catalog No. A20690

Rimacalib is a Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor, with IC50s of ~1 μM for CaMKIIα to ~30 μM for CaMKIIγ.

Technical details

Catalog Num	A20690
M. Wt	394.44
Formula	C22H23FN4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	215174-50-8
Synonyms	SMP 114, SMP114, SMP-114
SMILES	N=C(N1CCOCC1)NC2=CC([C@H](C3=CC=C(C4=CC=CC=C4)C(F)=C3)C)=NO2

Biological Activity

Rimacalib is a Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor, with IC50s of ~1 μM for CaMKIIα to ~30 μM for CaMKIIγ.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.35 mL	126.76 mL	253.52 mL
0.5 mM	5.07 mL	25.35 mL	50.7 mL
1 mM	2.54 mL	12.68 mL	25.35 mL
5 mM	0.51 mL	2.54 mL	5.07 mL

*The above data is based on the productmolecular weight 394.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Rimacalib

Technical details

Biological Activity

Preparing Stock Solutions