Mertansine
Catalog No. A20772
Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.
| Catalog Num | A20772 |
|---|---|
| M. Wt | 738.29 |
| Formula | C35H48ClN3O10S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 139504-50-0 |
| Synonyms | DM1; Maytansinoid DM1 |
| SMILES | C[C@]1([C@@](CC(N(C(C=C2C=C3OC)=C3Cl)C)=O)([H])OC([C@H](C)N(C)C(CCS)=O)=O)[C@H]([C@@H]([C@](OC4=O)([H])C[C@]([C@](/C=C/C=C(C)/C2)([H])OC)(N4)O)C)O1 |
Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.54 mL | 67.72 mL | 135.45 mL |
| 0.5 mM | 2.71 mL | 13.54 mL | 27.09 mL |
| 1 mM | 1.35 mL | 6.77 mL | 13.54 mL |
| 5 mM | 0.27 mL | 1.35 mL | 2.71 mL |
*The above data is based on the productmolecular weight 738.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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