Lapaquistat acetate

Catalog No. A20851

Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene.
Catalog Num A20851
M. Wt 645.14
Formula C33H41ClN2O9
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 189060-13-7
Synonyms TAK-475, TAK475, TAK 475
SMILES O=C(O)CC1CCN(C(C[C@@H]2C(N(CC(C)(C)COC(C)=O)C3=CC=C(Cl)C=C3[C@@H](C4=CC=CC(OC)=C4OC)O2)=O)=O)CC1
Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.5 mL 77.5 mL 155.01 mL
0.5 mM 3.1 mL 15.5 mL 31 mL
1 mM 1.55 mL 7.75 mL 15.5 mL
5 mM 0.31 mL 1.55 mL 3.1 mL

*The above data is based on the productmolecular weight 645.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.