Diclofensine hydrochloride

Catalog No. A20923

Diclofensine hydrochloride (Ro-8-4650 hydrochloride) is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively.
Catalog Num A20923
M. Wt 358.69
Formula C17H18Cl3NO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 34041-84-4
Synonyms Ro 8-4650 hydrochloride, Ro8-4650, Ro-8-4650
SMILES CN1CC2=C(C=CC(OC)=C2)C(C3=CC=C(Cl)C(Cl)=C3)C1.[H]Cl
Diclofensine hydrochloride (Ro-8-4650 hydrochloride) is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.88 mL 139.4 mL 278.79 mL
0.5 mM 5.58 mL 27.88 mL 55.76 mL
1 mM 2.79 mL 13.94 mL 27.88 mL
5 mM 0.56 mL 2.79 mL 5.58 mL

*The above data is based on the productmolecular weight 358.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.