ITX3

Catalog No. A20934

ITX3 is a specific and nontoxic inhibitor of the TrioN (N-terminal GEF domain of the multidomain Trio protein) with IC50 of 76 uM; inhibits TrioN-stimulated RhoG exchange in vitro.
Catalog Num A20934
M. Wt 371.45
Formula C22H17N3OS
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 347323-96-0
Synonyms ITX 3, ITX-3
SMILES O=C(/C1=C\C2=C(C)N(C(C)=C2)C3=CC=CC=C3)N4C(S1)=NC5=CC=CC=C45
ITX3 is a specific and nontoxic inhibitor of the TrioN (N-terminal GEF domain of the multidomain Trio protein) with IC50 of 76 uM; inhibits TrioN-stimulated RhoG exchange in vitro.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.92 mL 134.61 mL 269.22 mL
0.5 mM 5.38 mL 26.92 mL 53.84 mL
1 mM 2.69 mL 13.46 mL 26.92 mL
5 mM 0.54 mL 2.69 mL 5.38 mL

*The above data is based on the productmolecular weight 371.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.