RPR-260243
Catalog No. A20977
RPR-260243 is a novel activator of HERG; modifies HERG currents inhibited by dofetilide (IC50 = 58 nM); little effect on HERG current amplitude and no significant effects on steady-state activation parameters or on channel inactivation processes.
| Catalog Num | A20977 |
|---|---|
| M. Wt | 510.5 |
| Formula | C28H25F3N2O4 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 668463-35-2 |
| Synonyms | RPR260243, RPR 260243 |
| SMILES | O=C([C@H]1CN(CC#CC2=CC(F)=CC(F)=C2F)CC[C@H]1CCC(C3=CC=NC4=CC=C(OC)C=C34)=O)O |
RPR-260243 is a novel activator of HERG; modifies HERG currents inhibited by dofetilide (IC50 = 58 nM); little effect on HERG current amplitude and no significant effects on steady-state activation parameters or on channel inactivation processes.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.59 mL | 97.94 mL | 195.89 mL |
| 0.5 mM | 3.92 mL | 19.59 mL | 39.18 mL |
| 1 mM | 1.96 mL | 9.79 mL | 19.59 mL |
| 5 mM | 0.39 mL | 1.96 mL | 3.92 mL |
*The above data is based on the productmolecular weight 510.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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