AFP464
Catalog No. A20978
AFP464, is an active HIF-1α inhibitor with an IC50 of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator.
| Catalog Num | A20978 |
|---|---|
| M. Wt | 448.44 |
| Formula | C22H23F3N4O3 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 468719-52-0 |
| Synonyms | AFP 464, AFP-464 |
| SMILES | O=C(NC1=CC=C(C2=CC(C3=C(N)C(F)=C(C)C(F)=C3O2)=O)C=C1F)[C@@H](N)CCCCN |
AFP464, is an active HIF-1α inhibitor with an IC50 of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.3 mL | 111.5 mL | 223 mL |
| 0.5 mM | 4.46 mL | 22.3 mL | 44.6 mL |
| 1 mM | 2.23 mL | 11.15 mL | 22.3 mL |
| 5 mM | 0.45 mL | 2.23 mL | 4.46 mL |
*The above data is based on the productmolecular weight 448.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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