Domatinostat tosylate
Catalog No. A20986
Domatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).
| Catalog Num | A20986 |
|---|---|
| M. Wt | 619.71 |
| Formula | C30H29N5O6S2 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1186222-89-8 |
| Synonyms | 4SC-202, 4SC202, 4SC 202 |
| SMILES | O=C(NC1=CC=CC=C1N)/C=C/C2=CN(S(=O)(C3=CC=C(C4=CN(C)N=C4)C=C3)=O)C=C2.O=S(C5=CC=C(C)C=C5)(O)=O |
Domatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.14 mL | 80.68 mL | 161.37 mL |
| 0.5 mM | 3.23 mL | 16.14 mL | 32.27 mL |
| 1 mM | 1.61 mL | 8.07 mL | 16.14 mL |
| 5 mM | 0.32 mL | 1.61 mL | 3.23 mL |
*The above data is based on the productmolecular weight 619.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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