G-418 disulfate

Catalog No. A21002

G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

Technical details

Catalog Num	A21002
M. Wt	692.71
Formula	C20H44N4O18S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	108321-42-2
Synonyms	Geneticin sulfate; Antibiotic G-418 sulfate, G418, G 418
SMILES	O=S(O)(O)=O.O[C@@H]([C@@H]1O[C@@]([C@@H]([C@@H](O)[C@@H]2O)N)([H])O[C@]2([H])[C@H](O)C)[C@H]([C@@H](C[C@@H]1N)N)O[C@](OC[C@](C)(O)[C@@H]3NC)([H])[C@@H]3O.O=S(O)(O)=O

Biological Activity

G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

Solubility *

In vitro (25°C)	DMSO	Insoluble
	Water	Warmed: 92 mg/mL (132.81 mM)
	Ethanol	Insoluble
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.44 mL	72.18 mL	144.36 mL
0.5 mM	2.89 mL	14.44 mL	28.87 mL
1 mM	1.44 mL	7.22 mL	14.44 mL
5 mM	0.29 mL	1.44 mL	2.89 mL

*The above data is based on the productmolecular weight 692.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

G-418 disulfate

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions