MRT-83

Catalog No. A21020

MRT-83 is a potent antagonist of Smo, with an IC50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.
Catalog Num A21020
M. Wt 538.59
Formula C31H30N4O5
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1263131-92-5
Synonyms MRT83, MRT 83
SMILES COC1=C(OC)C(OC)=CC(C(NC(NC2=CC(NC(C3=CC=C(C4=CC=CC=C4)C=C3)=O)=C(C)C=C2)=N)=O)=C1
MRT-83 is a potent antagonist of Smo, with an IC50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.57 mL 92.83 mL 185.67 mL
0.5 mM 3.71 mL 18.57 mL 37.13 mL
1 mM 1.86 mL 9.28 mL 18.57 mL
5 mM 0.37 mL 1.86 mL 3.71 mL

*The above data is based on the productmolecular weight 538.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.