NBI-74330

Catalog No. A21158

NBI-74330 is a potent antagonist for CXCR3, and exhibits potent inhibition of (125I)CXCL10 and (125I)CXCL11 specific binding with Ki of 1.5 and 3.2 nM, respectively.
Catalog Num A21158
M. Wt 605.58
Formula C32H27F4N5O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 855527-92-3
Synonyms NBI74330, NBI 74330
SMILES O=C(N([C@@H](C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)C)CC4=CC=CN=C4)CC5=CC=C(F)C(C(F)(F)F)=C5
NBI-74330 is a potent antagonist for CXCR3, and exhibits potent inhibition of (125I)CXCL10 and (125I)CXCL11 specific binding with Ki of 1.5 and 3.2 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.51 mL 82.57 mL 165.13 mL
0.5 mM 3.3 mL 16.51 mL 33.03 mL
1 mM 1.65 mL 8.26 mL 16.51 mL
5 mM 0.33 mL 1.65 mL 3.3 mL

*The above data is based on the productmolecular weight 605.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.